Free access to the latest research
Welcome to the Obstetrics Resource Centre, with free access to the latest research in the field.
All content is independently selected by the Editors, Professor James O. Drife from Leeds, UK, and Professor Jim Thornton from Nottingham. The Obstetrics Resource Centre provides you with original articles, reviews, selected must-reads, lectures and a congress planner.
Selected EJOG Papers
Editor’s comment: Prof. James Drife: Do randomised trials change clinical practice?
In 2013 researchers in The Netherlands published the results of a multicentre randomised controlled trial (RCT) of a 12-day course of nifedipine following initial treatment of preterm labour. They concluded that such maintenance tocolysis did not appear to be beneficial. In this new study they report that in the participating centres the mean length of stay after a first admission with threatened preterm labour fell, not only after completion of the trial but also during the recruitment period. Participating in an RCT has the potential to change practice.
Impact of a randomized trial on maintenance tocolysis on length of hospital admission of women with threatened preterm labor in The Netherlands
Thomas S. de Lange, Carolien Roos, Kitty W.M. Bloemenkamp, Antoinette C. Bolte, Johannes J.J. Duvekot, Maureen T.M. Franssen, Marjolein Kok, Martijn A. Oudijk, Martina M. Porath, Joris A.M. van der Post, Ben Willem J. Mol
European Journal of Obstetrics & Gynecology and Reproductive Biology, pages 8 - 11
Editor’s comment: Prof. James Drife: Nomograms to predict preterm birth
Recently various nomograms have been published for the prediction of, for example, survival after endometrial cancer or vaginal birth after caesarean section. Two have been developed in France for the prediction of pretem birth – one to predict delivery within 48 hours of transfer and one to predict delivery before 32 weeks’ gestation. In this study in Vienna, two modified prediction models were developed and validated. They allow accurate assessment of the risk of delivery after threatened preterm labour, and an online calculator is available.
Mariella Mailath-Pokorny, Stephan Polterauer, Maria Kohl, Verena Kueronyai, Katharina Worda, Georg Heinze, Martin Langer
European Journal of Obstetrics & Gynecology and Reproductive Biology, pages 42 - 48
Editor’s comment: Prof. James Drife: Measuring cervical hardness or softness
Research continues into new ways of predicting preterm birth, to be used alongside ultrasound measurement of cervical length. The consistency of cervical tissue has long been part of the Bishop score and can now be assessed by elastography using a transvaginal ultrasound probe. Colour coding shows soft tissue as red and hard tissue as blue. In this prospective study of 72 women, the cervical elastography index in the first trimester appeared to be associated with obstetrical outcomes, irrespective of cervical length.
Laura Sabiani, Jean-Baptiste Haumonte, Anderson Loundou, Anne-Sophie Caro, Julie Brunet, Jean-Francois Cocallemen, Claude D’ercole, Florence Bretelle
European Journal of Obstetrics & Gynecology and Reproductive Biology, pages 80 - 84