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Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women

N Engl J Med. 2017 May 25;376(21):2043-2052.

Editor's comment: Prof. Jim Thornton: Oil is better than water

A randomised trial from the Netherlands among 1119 infertile women, compared hystero-salpingography with oil or water contrast medium. Ongoing pregnancies and live births were significantly higher in the oil contrast group. RR 1.37; 95% CI 1.16-1.61, and RR 1.38; 95% CI 1.17-1.64 respectively.