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Selected EJOG Papers
Peer-Reviewed Articles with editor titles and comments, selected by EJOG resource centre editor, James O. Drife, Emeritus Professor of Obstetrics and Gynaecology at the University of Leeds, UK.
All EJOG journal papers are available in full text format with PDFs of the complete papers.
Editor's comment: Prof. Tak Yeung Leung: Risk-based screening combined with a PCR-based test for group B streptococci diminishes the use of antibiotics in laboring women
About 12% pregnant women may carry group B streptococci around the time of the onset of labour. Routine antenatal screening for group B streptococci may not be feasible because of unexpected onset of labour. In such situation intrapartum PCR-based test may provides a rapid result for decision of prophylactic antibiotics. The sensitivity is 83% and the specificity is 97%.
Risk-based screening combined with a PCR-based test for group B streptococci diminishes the use of antibiotics in laboring womenEuropean Journal of Obstetrics & Gynecology and Reproductive Biology Volume 215, August 2017, Pages 188-192
Editor's comment: Prof. Tak Yeung Leung: Balloon catheters for induction of labor at term after previous cesarean section: a systematic review
While there are a number of studies on balloon catheters for induction of labor (IOL) in non-scarred uterus, its use for IOL in scarred uterus is not well studies, as illustrated from the systematic review by Kehl et al. With a limited sample size and retrospective analyses, Kehl demonstrated a moderate increase in the risk of uterine scar rupture (OR = 2.45) when balloon catheters were used. Further RCT is needed to confirm such risk.
Balloon catheters for induction of labor at term after previous cesarean section: a systematic review
Sven Kehl, Christel Weiss, Werner Rath
European Journal of Obstetrics & Gynecology and Reproductive Biology, September 2016, Pages 44 - 50
Editor’s comment: Prof. Tak Yeung Leung: Endometrial cancer can be accurately predicted by transvaginal ultrasonic measurement of endometrial thickness
With a cohort of 4383 women presented with postmenopausal bleeding, of whom 168 (3.8%) had endometrial cancer, a Hong Kong group has shown that transvaginal ultrasonic (TVS) measurement of endometrial thickness (ET) can achieve a satisfactory detection rate of endometrial cancer. The area under curve (AUC) and Youdens Index was respectively 0.92 (95% CI 0.88–0.96) and 0.71 (Sensitivity = 82.7%; Specificity = 88.3%; +ve LR = 6.38; −ve LR = 0.2). The performance of TVS in predicting endometrial cancer is significantly superior to that by patient’s history and characteristics. Training of TVS is important to ensure the accuracy of ET measurement and predictive power of this tool. http://www.ejog.org/article/S0301-2115(16)30210-X/fulltext
Alyssa Sze-Wai Wong, Chun Wai Cheung, Linda Wen-Ying Fung, Terence Tzu-Hsi Lao, Ben Willem J. Mol, Daljit Singh Sahota
European Journal of Obstetrics & Gynecology and Reproductive Biology, August 2016, Pages 220 - 224
Editor’s comment: Prof. Tak Yeung Leung: Beware of co-existing endometrial carcinoma in patients who are treated for atypical endometrial hyperplasia
A French group has looked into 32 patients who were initially diagnosed to have atypical endometrial hyperplasia (AEH) based on hysteroscopic resection products, and then subsequently underwent hysterectomy. Two out of these 32 cases (6.2%) was finally diagnosed to have coexisting endometrial carcinoma, while 6/32 (18.8%) cases had residual AEH, and the remaining 24/32 (75%) cases had no more AEH. Endometrial carcinoma cannot be totally excluded with hysteroscopic resection. Hysterectomy remains to be a definite treatment for AEH for those patients with no fertility wish. Close and long term follow-up is necessary if patients decline hysterectomy.
Risk of coexisting endometrial carcinoma in case of atypical endometrial hyperplasia diagnosed on total hysteroscopic resection
Audrey Pivano, Patrice Crochet, Xavier Carcopino, Ludovic Cravello, Léon Boubli, Aubert Agostini
European Journal of Obstetrics & Gynecology and Reproductive Biology, August 2016, Pages 210 - 213
Editor’s comment: Prof. Tak Yeung Leung:
Placenta previa is a major cause of massive postpartum haemorrhage. In a prospective observational study of 99 women with placenta previa diagnosed between 20 and 22 weeks of gestation, 44 had uterine isthmus completely open before 25 weeks (EO-previa), and 55 cases had it open after 25 weeks (LO-previa). The former group was more likely to have complete placenta previa at delivery (88.6% vs 47.3%, p < 0.001), emergency caesarean section due to active bleeding (48% vs 25%, p = 0.021), and massive haemorrage (>2500 ml) (25% vs 9%, p = 0.033).
Placenta previa with early opening of the uterine isthmus is associated with high risk of bleeding during pregnancy, and massive haemorrhage during caesarean delivery
M. Goto, J. Hasegawa, T. Arakaki, H. Takita, T. Oba, M. Nakamura, A. Sekizawa
European Journal of Obstetrics & Gynecology and Reproductive Biology, June 2016, Pages 7 - 11
Editor’s comment: Prof. Tak Yeung Leung:
Cervical cerclage may be a treatment option for women with cervical incompetence, but vaginal cervical cerclage is not very effective and transabdominal cerclage may be rather invasive. Laparoscopic cerclage may be an alternative. An observational cohort of 100 cases underwent simplified laparoscopic cervical cerclage (SLCC) in China shows a good outcome. Among 55 pregnancies which progressed beyond the first trimester, 53 of them resulted in a live birth (96.4%). The mean gestational age at delivery of this group of women was 37.5 ± 1.8 weeks. A randomized controlled trial may be needed to confirm the result.
Simplified laparoscopic cervical cerclage after failure of vaginal suture: technique and results of a consecutive series of 100 cases
Xiaowu Huang, Ning Ma, Tin-Chiu Li, Yan Guo, Dongmei Song, Yuting Zhao, Enlan Xia
European Journal of Obstetrics & Gynecology and Reproductive Biology, June 2016, Pages 146 - 150
Marlena S. Fejzo, Aromalyn Magtira, Frederic Paik Schoenberg, Kimber Macgibbon, Patrick M. Mullin
European Journal of Obstetrics & Gynecology and Reproductive Biology, June 2015, Pages 79 - 84
Gert J. van Baaren, Myrthe J.C.S. Peelen, Ewoud Schuit, Joris A.M. van der Post, Ben W.J. Mol, Marjolein Kok, Petra J. Hajenius
European Journal of Obstetrics & Gynecology and Reproductive Biology
Victoria Geenes, Jenny Chambers, Rshmi Khurana, Elisabeth Wikstrom Shemer, Winnie Sia, Dalvinder Mandair, Elwyn Elias, Hanns-Ulrich Marschall, William Hague, Catherine Williamson
European Journal of Obstetrics & Gynecology and Reproductive Biology, June 2015, Pages 59 - 63