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Editor’s comment: Prof. Tak Yeung Leung: Beware of co-existing endometrial carcinoma in patients who are treated for atypical endometrial hyperplasia

A French group has looked into 32 patients who were initially diagnosed to have atypical endometrial hyperplasia (AEH) based on hysteroscopic resection products, and then subsequently underwent hysterectomy. Two out of these 32 cases (6.2%) was finally diagnosed to have coexisting endometrial carcinoma, while 6/32 (18.8%) cases had residual AEH, and the remaining 24/32 (75%) cases had no more AEH. Endometrial carcinoma cannot be totally excluded with hysteroscopic resection. Hysterectomy remains to be a definite treatment for AEH for those patients with no fertility wish. Close and long term follow-up is necessary if patients decline hysterectomy.  

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Commentaries by Editor Prof. Jim Thornton