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Editor’s comment: Prof. Tak Yeung Leung: Endometrial cancer can be accurately predicted by transvaginal ultrasonic measurement of endometrial thickness

With a cohort of 4383 women presented with postmenopausal bleeding, of whom 168 (3.8%) had endometrial cancer, a Hong Kong group has shown that transvaginal ultrasonic (TVS) measurement of endometrial thickness (ET) can achieve a satisfactory detection rate of endometrial cancer. The area under curve (AUC) and Youdens Index was respectively 0.92 (95% CI 0.88–0.96) and 0.71 (Sensitivity = 82.7%; Specificity = 88.3%; +ve LR = 6.38; −ve LR = 0.2). The performance of TVS in predicting endometrial cancer is significantly superior to that by patient’s history and characteristics. Training of TVS is important to ensure the accuracy of ET measurement and predictive power of this tool.


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Commentaries by Editor Prof. Jim Thornton